Syphilis is a contagious disease caused by syphilis spirochete infection, which requires active treatment to be cured, and different types of syphilis are cured differently. Syphilis is divided into early (first, second) syphilis, late (third) syphilis, latent syphilis, syphilis in pregnancy. 1. Early syphilis: Diagnosed as one or two stages of syphilis without other systemic lesions, if the timely standardized treatment, can be cured. Most of the first stage syphilis within 1 year serologic test turn negative, second stage syphilis within 2 years turn negative. A small number of patients may relapse or be re-infected with syphilis. 2. Advanced (stage III) syphilis: The prognosis is unsatisfactory. Stage III syphilis often involves internal organs, affecting organ function and thus life and even life, and is the main cause of death. 3. Latent syphilis: Continuing for several years or decades without clinical symptoms, but if not timely diagnosis and treatment, may progress to stage III syphilis. The destruction of multiple systems or tissues of multiple organs in the whole body will lead to the damage of organ function and even endanger the life of the patient. 4. Syphilis during pregnancy: Syphilis spirochetes can infect the fetus, and if left untreated, it can cause miscarriage, preterm labor, stillbirth and stillbirth. Early detection and timely treatment, pregnant women can give birth to an uninfected fetus. Syphilis patients need to face the disease correctly, actively cooperate with the treatment, and strive for early recovery. Avoid sexual intercourse in daily life to prevent infecting others. Do not mix towels, basins and other personal belongings with others.