Generally, alcohol is not recommended after 24 hours of a tetanus shot. Since tetanus shot, especially tetanus toxoid, has allergic reaction, such as the performance of depression or irritability, pale or flushed, chest tightness or shortness of breath, cold sweating, nausea or abdominal pain, rapid pulse, blood pressure drop, and in severe cases of unconsciousness and weakness, if not rescued in time, it can be rapid death. Although the skin test or desensitization therapy before the injection, there is generally no allergic phenomenon, but the alcohol irritation is large, it is likely to aggravate the allergic reaction. And alcohol may affect the combination of antigen and antibody in the patient’s body, affecting the effect of the vaccine, so it is not recommended to drink alcohol after 24 hours of tetanus. If there is no discomfort for 3~7 days after vaccination, then you can drink alcohol in moderation. If there is any discomfort after vaccination, consult a doctor for timely and targeted treatment.