Colchicine cannot be applied externally, and its only route of use is by mouth. Colchicine is commonly used in the acute phase of gouty arthritis to relieve joint pain caused by the acute phase, and also to prevent acute attacks of recurrent gouty arthritis. Colchicine is not used as a topical medication. In the acute stage of gouty arthritis, you can choose to take colchicine orally, if the swelling and pain of joints are more obvious, you can take colchicine orally on the basis of the doctor’s advice with non-steroidal drugs for external application of creams, such as FUTALIN (the main component of the drug is diclofenac diethylamide) and so on, which will help to relieve pain more quickly, through the acute stage of arthritis. When taking colchicine, it should be noted that this drug may cause gastrointestinal manifestations such as diarrhea, vomiting, and in some patients even muscular and neurological lesions, bone marrow suppression. It is contraindicated for those with low myeloproliferative, hepatic and renal insufficiency. Precautions: When vomiting, diarrhea and other reactions occur, the dosage should be reduced, and in serious cases, the drug should be stopped immediately. Bone marrow hematopoietic insufficiency, severe heart disease, renal insufficiency and gastrointestinal disorders should be used with caution. Regularly check the blood and liver and kidney functions during the use of the drug. Colchicine must be used under the supervision of a doctor, do not use privately.