The third injection here should refer to the third injection of New Crown Vaccine. Thyroid nodules can usually be vaccinated with the third injection of New Crown Vaccine, but it is not recommended if there are obvious symptoms of hyperthyroidism or hypothyroidism, and it needs to be judged according to the patient’s specific situation. The injection of New Crown Vaccine generally has no effect on benign thyroid nodules, and the third injection of New Crown Vaccine can be administered. However, if the patient has obvious symptoms of hyperthyroidism or hypothyroidism, it is not recommended to receive the New Crown vaccine, and can wait until the condition is stabilized before considering vaccination. Whether patients with thyroid nodules can receive the third dose of the New Crown Vaccine can be decided by a specialized doctor in the Department of Endocrinology after evaluation.