Back pain after sleeping after lung nodule surgery may be caused by inflammatory lung irritation causing back pain, or it may be caused by physical factors such as overexertion and poor sleeping position. Depending on the cause, the treatment will be different, including symptomatic treatment, medication and so on. 1. Lung inflammation stimulation: after lung nodule surgery, the blood seepage from the lung tissue in the chest cavity has not been completely absorbed, which is prone to lung infections, and the localized infections will lead to possible separation of the sutured area. Therefore, when back pain occurs, it is recommended to do CT review, if the combined infection, disinfection and sterilization in the surgical area, and oral anti-inflammatory pain medication, such as amoxicillin, ibuprofen extended-release capsules, tramadol extended-release tablets, etc., if necessary. 2. Physiological factors: overwork, poor sleeping posture and other physiological factors, also often lead to back pain, it is recommended that patients pay attention to rest, avoid exertion, and develop good sleeping habits. There are many causes of back pain after surgery for pulmonary nodules, we should discover the cause of the disease under the guidance of physicians, early diagnosis and early treatment to avoid aggravation of the condition.