Tadalafil with Dapoxetine is generally used to treat erectile dysfunction and premature ejaculation in men. Tadalafil is an oral medication for adult males, prohibited for those under 18 years of age, and can be used to treat erectile dysfunction in men. Sexual stimulation is required for tadalafil to take effect after use, and a few patients may experience adverse reactions such as headache and indigestion after using the drug. Dapoxetine is a selective 5-hydroxytryptamine reuptake inhibitor, can be used to treat men with premature ejaculation, minors, pregnant women and lactating women are prohibited. Other medications should be discontinued while taking the drug, and it generally needs to be contraindicated in people who have recently had a heart attack or have severe kidney damage. Clinical use of the above two drugs in combination is usually due to the coexistence of erectile dysfunction and premature ejaculation, and it should be noted that if the combination is to be used, it must be done under the supervision of a doctor.