Patients with swollen legs in the afternoon are usually seen to have kidney disease, which will cause abnormal kidney function. In this case, it is recommended that the patient must go to the hospital in time for relevant examinations, such as ultrasound examination of the kidneys or magnetic resonance examination of the kidneys, which can generally clarify the diagnosis. When the diagnosis is clear, symptomatic treatment must be carried out in time to avoid serious complications. In addition, it is also possible that patients may be sedentary or standing for a long time, which may also lead to swelling of the legs in the afternoon. This is due to the restriction of venous return in the lower limbs, which leads to blood stagnation, causing local tissue edema and thus causing swelling of the legs in the afternoon, and it is recommended that patients improve this swelling of the legs in the afternoon through appropriate exercise.