Artificial liver, also known as artificial liver support system, is a blood filter constructed with man-made high-tech materials that simulate the human liver. It can replace part of the liver’s excretory function and filter out part of the jaundice, toxins and metabolites gathered in the body through the artery-filter-vein circuit to reduce the burden on the liver and give the damaged liver cells a chance to be repaired and regenerated, so as to achieve the purpose of curing severe hepatitis. Artificial liver technology is specialized in blood detoxification, using blood exchange to replace the toxins in the plasma of the patient, that is, to replace the patient’s plasma containing toxins with healthy plasma, which can be about 50% of the whole body’s plasma each time. Artificial liver for liver failure patients only play the role of extracorporeal support and functional replacement, can be divided into non-biological and biological artificial liver. Artificial livers can be used for acute and chronic liver failure caused by severe hepatitis, liver failure occurring after surgery, or before and after liver transplantation.