Clinically there is no such thing as 6 precursor manifestations of uremia. The precursors of uremia patients can be manifested as decreased urine output, swelling of the body, loss of appetite, insomnia, itching of the skin, and the emergence of a bad taste in the mouth, etc. However, these lack of specificity may also be the early symptoms of other diseases.
1. Decreased urine output: Due to the dysfunction of kidney, the kidney’s filtering ability of urine becomes worse, which will affect the urine volume and make the urine output decrease.
2. Swelling: impaired kidney function will cause water and salt metabolism disorders in the body, so that excess water can not be metabolized, which leads to edema in the eyelid area of the patient, and eyelid edema is more obvious in the morning.
3. Loss of appetite: Kidney function damage will affect the urease enzyme to decompose urea, resulting in the decomposition of urea to produce a large number of ammonia-like substances. Ammonia will cause irritation to the mucous membrane of the gastrointestinal tract, which will cause gastrointestinal inflammation, indigestion and loss of appetite.
4. Insomnia: Uremia will lead to peripheral nerve lesions, affecting the mental state, making patients suffer from insomnia, poor concentration, memory loss and other symptoms.
5. Itchy skin: impaired kidney function will affect the metabolism of substances, resulting in a large amount of residual waste toxins in the body, which will cause skin irritation, leading to itchy skin.
6. Oral odor: As bacteria can decompose urea in saliva to produce ammonia, resulting in exhaled gas filled with the smell of urine, so the breath will produce a bad smell.
If the above symptoms occur, should cause great attention, timely to the regular hospital to the diagnosis.