Sudden sweating in the limbs may be related to physiologic factors, if there has been no eating for a long time. It may also be caused by pathological factors, such as perimenopausal syndrome, diabetes mellitus, hyperthyroidism, anemia and other factors. 1. Perimenopausal syndrome: when women enter menopause, the hormone levels in the body change, and the ovaries gradually decline leading to menstrual disorders and menopause, and the patients may have irritable moods, irritability, sweating, and weakness. 2. Diabetes: Inappropriate use of hypoglycemic drugs in patients with diabetes can cause hypoglycemic reaction, which is also the main cause of sweating and weakness. 3. Hyperthyroidism: Hyperthyroidism is associated with increased basal metabolic rate and increased sensitivity of the nervous system. 4. Anemia: Anemia caused by various factors, patients may have symptoms such as pale nails, lips and mouth, weakness and sweating. Weakness of the limbs, sudden sweating, may be related to a variety of factors, it is recommended to eat properly, if necessary, go to the hospital to clarify the cause, follow the doctor’s instructions for treatment.