Diffuse thickening of the bladder wall refers to the compensatory hyperplasia of the bladder wall muscles, which is mainly seen in chronic cystitis, prostate hyperplasia or bladder stones and other diseases. 1. Chronic cystitis: When chronic cystitis occurs, its inflammatory substances will stimulate the bladder mucosa, which can cause congestion and edema of the bladder mucosa, and long-term stimulation of inflammatory substances will lead to compensatory hyperplasia of the bladder wall muscles, which is higher than the normal level, thus resulting in the phenomenon of diffuse thickening of the bladder wall. 2. Prostatic hyperplasia: it can cause obstruction of the bladder outlet, which in turn causes the muscle contraction of the bladder wall to increase, thus diffuse thickening of the bladder wall can occur. 3. Bladder stones: can cause stimulation of bladder contraction, long-term bladder contraction can cause compensatory hyperplasia of the bladder wall muscle, thus causing the symptoms of diffuse thickening of the bladder wall. Diffuse thickening of the bladder wall may also be caused by other factors, it is recommended that patients go to the regular hospital in time for treatment, and strive for early recovery.