IVF does not necessarily require a non-invasive DNA test. Non-invasive DNA is a test in which the mother’s blood is drawn during the 11-13th week of pregnancy to check for free fetal DNA in the blood. However, this test has some limitations, because it can only check the situation of trisomy 13, 16 and 18, but not other situations. Therefore, pregnant women can do non-invasive DNA, but they also need to do NT test in 11-13 weeks of pregnancy. If the mother-to-be undergoes NT examination and amniocentesis, she can disregard non-invasive DNA because NT examination can detect a wider range of fetal malformations, and amniocentesis can be done if necessary, which can complement each other and make the whole system of monitoring fetal malformations appear more complete. Therefore, do not mistakenly think that there is no need to do other tests if you have non-invasive DNA, which is actually a one-sided view. Because non-invasive DNA can only check for three types of fetal malformations, NT and amniocentesis may provide more information about fetal malformations, which is good for preventing the birth of malformed fetuses. After having NT and non-invasive DNA, it is important to follow your obstetrician’s advice and have prenatal checkups as scheduled to rule out fetal malformations. If the patient has already had a non-invasive DNA test, he or she will still need to have an NT test and necessary amniocentesis during the child’s development.