Tenofovir is known generically as tenofovir disoproxil fumarate tablets, and the recovery time after kidney injury cannot be determined. Rare renal impairment, renal failure, and proximal tubular lesions have been reported in persons using tenofovir disoproxil fumarate, and bone abnormalities have been reported, and it is recommended that renal function be monitored in persons taking this product. The dosing interval of tenofovir disoproxil fumarate should be adjusted and renal function should be closely monitored in all individuals with creatinine clearance less than 50 mL/min. Currently, the dose of the drug may be adjusted according to dose-adjustment guidelines for persons with renal impairment receiving tenofovir disoproxil fumarate, but there are no available safety or efficacy data for this population. Tenofovir disoproxil fumarate tablets can be recovered from kidney injury and should be taken as directed by a doctor for specific conditions. Before taking the drug must carefully read the instructions to understand the precautions of the drug, as well as contraindications and other drug information, allergic to any component of the drug should be prohibited. At the same time in the process of medication should pay attention to regular review or follow-up, so that the doctor adjusts the medication according to the condition and kidney injury.