Pain at the junction of the shoulder and neck can be caused by the following diseases: first, cervical spondylosis, which occurs more often in the elderly, is accompanied by upper limb muscle weakness, numbness, and limited movement, which is related to strain and is caused by local nerve root compression. Secondly, there are also patients with local subcutaneous occupying lesions, such as subcutaneous lipomas or fibroids, which may cause localized pain and also manifest as obvious bulging masses with clear borders and good mobility, and require further surgical treatment to remove the lesions if necessary.