Appendicitis can be treated with anti-inflammatory drugs in the early stages, but once appendicitis is diagnosed, appendectomy is recommended as soon as possible. Mild appendicitis can be treated with anti-inflammatory drugs. To control the development of the disease, you can generally follow the doctor’s instructions to use cephalosporin anti-inflammatory drugs, such as cefaclor, amoxicillin, or broad-spectrum antibiotics, such as cotrimoxazole, levofloxacin and so on can relieve the symptoms. Drug therapy is only suitable for simple appendicitis, the early stage of acute appendicitis, patients who do not undergo surgical treatment, poor general condition or objective conditions do not allow it, accompanied by other serious organic diseases, and patients with contraindications to surgery. The main measures include selection of effective antibiotics and rehydration therapy. Antibiotic selection needs to cover both aerobic and anaerobic flora of the intestinal tract, and cephalosporin antibiotics combined with metronidazole are most commonly used clinically. Once appendicitis is diagnosed, appendectomy is recommended as soon as possible, and pharmacologic anti-infective and symptomatic treatment is required. Commonly used surgical options are laparoscopic appendectomy and open appendectomy. Early surgery is safe, simple and reduces the incidence of immediate or long-term complications. If treated promptly, the prognosis is good. Patients with appendicitis are advised to seek timely treatment to avoid delays. If the early antibiotic treatment is not effective and the condition tends to worsen, the patient should go to the hospital in time for intravenous antibiotics (e.g. ceftriaxone sodium, levofloxacin, etc.) or surgical treatment.