Mosquito bites large swelling should go to the regular hospital in time, under the guidance of a professional doctor to take orally or apply drugs, as well as physical therapy to deal with. 1. Oral medication: mosquito bites large swelling belongs to the performance of insect bite dermatitis. Antihistamines, such as diphenhydramine and loratadine, can be taken as prescribed by the doctor. If the allergic reaction is serious, you can follow the doctor’s instructions to take short-term glucocorticosteroids, such as prednisone and other anti-inflammatory, swelling. If the lesions are associated with secondary infection, it is recommended to take amoxicillin, cephalosporin and other drugs as prescribed by the doctor. 2. Smear drugs: for mosquito bites produced a large area of swelling, but also in the lesions can be coated with medical advice in the Dinaid cream, hydrocortisone butyrate cream, halomethasone cream and other drugs anti-inflammatory, antipruritic, anti-allergic. When the mosquito bite swelling is more relieved, you can also apply local glycerin lotion to stop itching. 3. Physical therapy: If the symptoms of mosquito bites and swelling are more serious, you can also use the semiconductor laser to reduce swelling. In daily life, you can also use cold compresses to relieve local pain, itching and other discomfort. In short, if the mosquito bites large swelling, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor, choose the appropriate treatment program.