With urine concentration, there is no increase in urinary protein, but there is an increased rate of positive findings on routine urinalysis. Urine concentration is usually observed in morning urine, especially if the urine has been in the bladder for more than four hours, and is usually confirmed by a 24-hour urine protein quantification. The density of the urine multiplied by the volume equals the mass. When the urine protein quantification is greater than 3.5g/24h, it is called massive proteinuria. When the urine protein is more than 150mg/24h is known as having urinary protein, it is necessary to determine the situation of urinary protein through the 24-hour urinary protein quantification, combined with the urine routine together, can not simply through the urine routine to determine the situation of urinary protein.