Dry syndrome is an autoimmune disease characterized by damage to the exocrine glands and manifested as dry eyes, dry mouth and dry skin. Because the cause of dry syndrome is still unclear, it is generally incurable, but if early intervention is made, clinical symptoms can be effectively improved. The purpose of treatment for dry syndrome is mainly to avoid damage to the oral cavity and local dryness of the eyes for a long time, and to prevent connective tissue damage to other tissues and organs of the body. Generally, it is relieved and improved by improving lifestyle, symptomatic treatment and immunotherapy: 1. Improving lifestyle: drinking more water and avoiding eye strain caused by prolonged visualization can usually temporarily relieve the symptoms. Usually, you should pay attention to oral and eye hygiene, rinse your mouth regularly to prevent oral infection. When the room is dry, you can use a humidifier to keep the room at the right humidity; 2, symptomatic treatment: if dry eyes appear, you can improve through eye drops, clinical dry mouth and dry eyes can also use artificial saliva, artificial tears and other preparations to achieve part of the alternative role. When joint pain occurs, non-steroidal anti-inflammatory drugs can be taken under the guidance of a doctor to relieve, commonly used are indomethacin, celecoxib, etc.; 3, immunotherapy: interstitial pneumonia, osteoarthritis and liver and kidney function damage, can be treated with glucocorticoids combined with immunosuppressants. If conventional drug therapy is not effective, other drugs such as biologics can be applied for treatment.