Fever reducers for anal plugs include acetaminophen suppositories, indomethacin suppositories, dextro-ibuprofen suppositories, and diclofenac sodium suppositories. 1. Acetaminophen suppositories can inhibit prostaglandin synthesis and thus play the role of antipyretic and analgesic, mainly used for children’s common cold, influenza fever. It can also relieve toothache, muscle pain and migraine. 2. Indomethacin suppository is a non-steroidal anti-inflammatory drug with anti-inflammatory, antipyretic and analgesic effects, which is used for relieving fever, muscle pain and arthralgia. 3. Dextro Ibuprofen Suppository also belongs to non-steroidal anti-inflammatory drugs, used for children’s upper respiratory tract infections, pediatric colds, acute pharyngitis caused by fever, pain. 4. Diclofenac sodium suppository is a non-steroidal anti-inflammatory drug of phenylacetic acid class, with antipyretic and analgesic effects, used for rheumatoid arthritis, post-surgical pain and fever caused by various reasons. Stuffing the anus with a variety of types of antipyretic drugs, but can not be used at will, all need to be standardized under the guidance of a doctor.