Lowering bilirubin requires first identifying the cause of the disease and treating it accordingly. Elevated bilirubin may be related to cholecystitis, bile duct stones, hepatitis and other diseases. It is recommended that patients go to the hospital in time and complete the relevant examinations. 1. Cholecystitis: patients may experience pain and discomfort in the right upper abdomen, nausea, vomiting and other symptoms. Total bilirubin may be high through blood biochemistry examination. It can be treated with medicines such as cholestyramine tablets, clindamycin, atropine, scopolamine and so on as prescribed by doctors. 2. Choledocholithiasis: patients may have abdominal pain, jaundice, chills, high fever and other symptoms. High total bilirubin may appear through blood biochemical examination. Cephalosporin, metronidazole, ursodeoxycholic acid and other drugs can be used as prescribed by the doctor. 3. Hepatitis: patients may have nausea, vomiting, anorexia, fatigue, yellowing of skin and sclera, abdominal discomfort and other symptoms. Increased bilirubin can be seen through liver function tests. Can follow the doctor’s instructions to use reduced glutathione, glycyrrhizic acid preparation, bisabolol and other drugs. It is recommended that the patient go to the hospital in time, choose the appropriate treatment under the guidance of the doctor, and after controlling the cause of the disease, the bilirubin will naturally decrease.