Both loratadine tablets and dicloretadine are used to treat allergic rhinitis. Non-allergic rhinitis does not require the use of such medications. Loratadine belongs to the second generation of antihistamines. Histamine is a neurotransmitter with pro-inflammatory effects, and when the body is subjected to some kind of stimulation, mast cells release histamine, which causes allergic rhinitis, allergic skin symptoms and other diseases. Taking loratadine provides rapid relief from allergy-induced sneezing, runny nose, itchy nose, itchy eyes, and skin allergy symptoms. Common adverse reactions include fatigue, drowsiness, headache and dry mouth, nausea, etc. Less common are symptoms such as panic and abnormal liver function. Desloratadine belongs to the third generation of antihistamines, because Desloratadine is a metabolite of loratadine, so, after taking Desloratadine than loratadine onset of action time is faster, the effect is also stronger, the effect of the drug to maintain a longer period of time, and relatively fewer than loratadine side effects, such as drowsiness symptoms reduced. However, it should be used with caution in children under 12 years of age. Rhinitis patients are reminded that whether applying loratadine or dicloretadine to treat allergic rhinitis, it is important to use it under the guidance of a doctor so as to ensure the safety of the medication.