Embryos with chromosomal abnormalities and frozen embryos cannot be used.
Chromosomal abnormalities in embryos mean that all the chromosomes of the embryo are abnormal and cannot be used, leading to developmental abnormalities and miscarriage after pregnancy. Embryonic chromosome abnormalities usually result in spontaneous abortion during the early stages of pregnancy and may be accompanied by birth defects even if the fetus continues to survive.
For embryos with chromosomal abnormalities, it is recommended that both spouses undergo a chromosomal test to determine if there are any abnormalities and to target treatment. If no chromosomal abnormality is seen in both spouses and the embryo has chromosomal abnormality, it may be due to age, environment and other factors.
For couples with chromosomal abnormalities and who have fertility requirements, it is recommended to undergo third-generation IVF, which can try to avoid foetal arrest and fetal developmental abnormalities caused by chromosomal abnormalities in embryos.