Sudden ear pain in the middle of the night, this situation needs to go to the Department of Otorhinolaryngology, you can hang up the emergency room of the Department of Otorhinolaryngology. After the consultation, routine blood tests and otoscopy are needed to help make a preliminary judgment of the condition. Most patients are due to acute inflammatory reactions, such as acute otitis media, acute otitis externa, and some patients are due to herpetic tympanitis. In terms of medication, currently more commonly used is oral medication, you can choose oral cephalosporin or penicillin antibiotics, some patients also need to use ear drops for treatment, more commonly used is levofloxacin hydrochloride ear drops, all belong to the prescription class of drugs, need to be in the otorhinolaryngology under the guidance of a doctor to use the drug, and need to be regular follow-up, observation of the effect.