The main ingredient of Uspermine is a combination of estrogen and progestin, but Uspermine has its own independent characteristics, for example, the progestin is the application of drospirenone, which has an anti-estrogen effect, so Uspermine rarely has water and sodium retention and obesity in the process of use. In addition, the phenomenon of discoloration on the face rarely occurs, mainly because the progesterone in Eusebio plays a role. Before taking Eusemide, you must do the corresponding examination to exclude uterine fibroids and breast enlargement and to exclude the possibility of thrombotic diseases before giving the medicine, because Eusemide contains estrogen, if patients with uterine fibroids often take Eusemide, it may cause the growth of fibroids to accelerate, which may cause serious consequences.