Laboratory tests: When the initial diagnosis or definitive pregnancy is made, the following evaluations are recommended: 1. Physical examination, including assessment of blood pressure. 2. Examination of renal function, including glomerular consideration rate, urine routine, and urine protein to urine creatinine ratio. 3.Blood routine, liver and kidney function. 4.anti-Ro/SSA and anti-La/SSB. 5.Lupus anticoagulant and anticardiolipin antibody. 6.anti-dsDNA. 7.Complementation test ( C3 and C4). Monthly monitoring of platelet count and blood cell count is recommended during the first 6 months of pregnancy. At the end of each third trimester of pregnancy, the following assessments are recommended: determination of glomerular consideration rate, urine protein to urine creatinine ratio. Anticardiolipin antibodies. Complement anti-dsDNA. Women with Ro/SSA and/or La/SSB antibodies have an increased risk of fetal congenital heart block, but monitoring by echocardiography is more beneficial. Its purpose is to detect congenital heart block early and intervene in its development with pharmacological treatment. Other tests: Fetal monitoring: women with sle can increase the risk of intrauterine developmental arrest and preterm delivery, therefore, regular ultrasound monitoring once a month should be requested starting at the initial consultation to assess gestational age.