There is no quick relief for calf soreness and swelling disease, first of all, it needs to be clearly diagnosed, such as physiological, lumbar disc herniation, calf deep vein thrombosis, etc., which can be relieved after causative treatment, medication and surgery. 1. Physiological factors: If the calf is sore and swollen due to lactic acid accumulation after over-exertion, exercise, etc., it can be relieved after 2 to 3 days of sufficient rest, hot compresses and massage. 2. Lumbar disc herniation: the herniated disc compresses the nerve root, resulting in leg soreness, you can apply ibuprofen and other analgesic under the guidance of the doctor, and in serious cases, you need to consider surgical treatment, such as discectomy. 3. Calf deep vein thrombosis: due to insufficient blood supply and oxygen supply leading to soreness and swelling of the calves, anticoagulation and thrombolytic therapy such as rivaroxaban and low molecular heparin can be applied to alleviate the pain. It is recommended that people with sore and swollen calves should consult a doctor in time to find out the cause and standardize the treatment under the doctor’s guidance.