Keloid scars are classified as superficial keloid scars, hyperplastic keloid scars, atrophic keloid scars, and keloid scars. There are many non-surgical treatments for keloid scars, and the treatment should be selected with the patient’s physical status and the characteristics of the scar. The commonly used non-surgical treatments in clinical practice include: compression therapy, silicone gel, medication, laser, radiation therapy, etc. The combination of one or more non-surgical treatment methods, especially non-invasive methods such as compression therapy and silicone gel, is recommended in clinical practice. Compression therapy is commonly used for post-burn hyperplastic scars to promote the maturation of the scar and make it thinner and softer. It is generally recommended to start treatment within 6 months of scar formation, with compression therapy for 18-24 hours per day until the scar matures; stopping too soon can cause the scar to recur. Silicone gel is an important method to prevent and treat proliferative scarring, improve itching and pain, and reduce the recurrence rate of scarring. Silicone gel can be made into liquid, gel, or film, which is easy and painless to use. Care should be taken to clean the film and skin during use to avoid maceration and itching. Medication includes local injections and topical application. Injection therapy can effectively improve the symptoms of itching and pain of keloid scars, and reduce the volume of keloid scars and make them thinner and softer, which is currently one of the most important non-surgical treatments for hyperplastic keloid scars. It is widely believed that the effect of corticosteroid combined with pentafluorouracil injection treatment appears early, reduces the amount of single dose and reduces the incidence of side effects, such as skin atrophy and pigmentation changes. Topical application of medications, mostly creams or gels made of plant extracts (e.g. onion extract/heparin gel, Centella asiatica, etc.), is effective in improving the texture and relieving the symptoms of scarring. Lasers are gaining more and more attention in the treatment of proliferative scars. Specific wavelengths of laser can selectively destroy the blood supply of scar tissue, thus inhibiting the proliferation of scar tissue. 585nm wavelength pulsed dye laser is commonly used in clinical practice, which can effectively improve the texture and congestion of scar tissue, etc. When combined with local injection treatment, better treatment results and fewer side effects are often obtained. The most common post-laser side effects are transient skin purpura, hypopigmentation and hyperpigmentation. For recalcitrant keloids, postoperative radiation therapy can also be used to assist in controlling their recurrence. Radiation therapy is often administered early in the postoperative period.