Glipizide extended-release tablets can be supplemented with meals, the drug is a long-acting extended-release tablets, it is recommended to take before breakfast, can continue to lower sugar, the specific use of medication should follow the doctor’s instructions. Glipizide extended-release tablets are swallowed whole, the drug is a long-acting extended-release tablets, about 11.6 ± 5.54 hours to reach the maximum blood concentration, it is recommended to take 30 minutes before breakfast, can continue to lower sugar, if you forget to take the drug before breakfast, you can make up for taking after breakfast. Glipizide extended-release tablets are indicated for mild to moderate type 2 diabetes mellitus that cannot be controlled by dietary therapy alone. The visible adverse effects of this product include epigastric bloating, nausea, headache, skin irritation, and hypoglycemia. The drug is contraindicated in people who are allergic to the product, people with type 1 diabetes, diabetes with ketoacidosis, severe burns, infections, trauma, leukopenia, liver and kidney insufficiency. Glipizide extended-release tablets should be used under the supervision of a physician.