After surgical treatment, esophageal cancer patients may face lung infection, at this time, it is necessary to choose appropriate antibiotic treatment for patients to control lung infection. Lung infection is one of the common postoperative complications of esophageal cancer patients. Physicians need to adopt appropriate antibiotics for anti-infection treatment according to the comprehensive health condition of patients, and cephalosporins or quinolones are commonly used in clinic. When esophageal cancer patients have lung infection, they should go to hospital for treatment in time.