Povidone-iodine has certain contraindications during use, if allergic to povidone-iodine can not be used, and oral use is strictly prohibited. Povidone-iodine is a broad-spectrum biological disinfectant with good bactericidal effect, and the irritation to the skin is relatively small, and generally no adverse reactions after external use. It can be used to disinfect skin or mucous membranes, and can also disinfect burns and wounds. However, there are certain contraindications during use, if allergic to iodophor, it can not be used, and belongs to the topical drugs, prohibited oral use, in the oral use of the relevant reactions may occur poisoning, such as nausea, vomiting, abdominal pain and so on. The surface of the patient’s skin can not be directly rinsed with water when the wound appears, it is easy to become infected, you can use iodophor to rinse, to effectively disinfect and sterilize.