Leg fatigue is considered to be related to muscle strain, lumbar disc herniation, fasciitis and other causes. It can be best treated by general treatment, physical therapy, medication and surgery according to the cause. 1. Muscle strain: such as walking too much, over-exercise, standing for a long time, etc., these activities will cause leg muscle strain and leg fatigue. At this time, you need to pay attention to rest, you can use hot compresses, massage, warm water bath and other methods of treatment, usually can be quickly recovered. 2. Lumbar intervertebral disc herniation: when the protruding intervertebral disc causes pressure on the nerve root, it will also cause leg fatigue, and there will be numbness, weakness and other symptoms. Normally, we should pay attention to maintenance, with heat therapy, electrotherapy, traction and other methods of treatment. If the nerve compression is serious, it can be treated by surgery, such as minimally invasive laminectomy. 3. Fasciitis: Inflammation of leg muscle fascia can also cause leg fatigue. Usually pay attention to rest, pay attention to local warmth, avoid overwork. Non-steroidal anti-inflammatory drugs, such as diclofenac sodium, can be applied to the treatment. Can also be combined with hot compresses, massage and other methods of treatment, can be effective in improving the symptoms. When leg fatigue occurs, you can go to the hospital to identify the cause of the disease, and then targeted treatment. The above drugs need to be applied under the guidance of a physician, avoid self-medication.