The main lesion of chronic glomerulonephritis is characterized by insidious onset and slow progression, which may have different degrees of renal function decline and eventually lead to chronic renal failure. Chronic glomerulonephritis is a group of glomerular diseases with hematuria, proteinuria, edema and hypertension as the main manifestations. Often the onset of the disease is insidious, patients do not have any symptoms, and need to be detected through relevant examinations. The patient’s condition is prolonged and slowly progresses, and as the disease progresses, renal function gradually declines, eventually leading to chronic renal failure. There are various types of pathology, mainly mesangial proliferative glomerulonephritis, mesangial capillary glomerulonephritis, membranous nephropathy, focal segmental glomerulosclerosis and so on. Patients with chronic glomerulonephritis need to have regular checkups of urine routine and renal function, etc., and under the guidance of doctors, carry out reasonable treatments to try to delay the progression of kidney disease.