The correct name for Sacubitril is Sacubitril Valsartan Sodium Tablets. The instructions for this product do not specify side effects after long-term use, but adverse reactions such as angioedema, hypotension, hyperkalemia, and renal impairment may occur after taking this medication. Sacubitril valsartan sodium tablets are indicated in adult patients with chronic heart failure to reduce the risk of cardiovascular mortality and morbidity in patients with heart failure. It may be used in place of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor antagonists (ARBs) in combination with other medications for the treatment of heart failure. It is contraindicated in patients with hypersensitivity to the active ingredient of sacubitril valsartan sodium tablets, co-administration with ACEIs is prohibited, and this drug must be taken only after 36 hours of cessation of ACEI therapy, in patients with a history of angioedema associated with ACEI or ARB therapy, in patients with hereditary or idiopathic angioedema, and in patients with severe hepatic impairment, and in patients with mid- to late-stage pregnancy. If you need to use this drug, please consult a professional doctor, follow the doctor’s instructions, and use the drug reasonably.