Penicillin injections in the buttocks are too painful, and it is possible that the injection site is too shallow. For some long-acting penicillin, the injection needs to be pushed at high pressure and in a short period of time, which may form deep fluid accumulation as well as hematoma. For such cases, patients need to do microwave heat therapy or high frequency heat therapy if necessary to promote the absorption of deep fluid. For normal people, if it is penicillin injection, you can choose to change to intravenous infusion, which will have a significant improvement for the relief of hip pain. Intravenous infusion of the drug is also better absorbed than intramuscular injection, but it should be noted that penicillin is now used less often in clinical practice. With the presence of methicillin-resistant staphylococci, the effect of penicillin use may be greatly reduced. Clinically, penicillin is now used sparingly, and if anti-inflammatory or antibacterial treatment is needed, cephalosporin antibiotics can be chosen for priority infusion.