Pearly penile papules, usually do not require treatment. If treatment is adhered to, methods include cryotherapy, surgical excision and laser therapy. 1. Cryotherapy: freezing and destroying the target tissue through low temperature to make it necrotic and detached, and there may be swelling, pain and other discomforts after the operation. 2. Surgical excision: if accompanied by long foreskin, circumcision is feasible, which can help to reduce the number of pearl rash. 3. Laser therapy: the main application of carbon dioxide laser, through the high energy generated by the laser directly target tissue gasification, cutting, the advantages of short time, quick recovery after surgery, is currently used more treatment. It is recommended to go to the hospital for treatment under the guidance of the doctor.