Pulse Ning Granules effect, mainly by the patient’s condition is decided, symptomatic treatment can receive good results. It is mainly used for the treatment of gangrene (at first cold and numbness of the limbs, then necrosis of the toe joints, black rot and ulceration, long time no healing), stroke, etc. Pulsatilla Granules, mainly consists of hyssop, xuan shen, honeysuckle and dendrobium. It has the effect of clearing heat and nourishing yin, activating blood circulation and removing blood stasis. It can treat gangrene caused by heat and poison injuring yin, yin deficiency and internal heat, and blood stasis, with burning pain, redness, swelling and ulceration of limbs, especially at night, or gangrene, with red texture, scarce moss, and fine pulse (the pulse becomes narrower and finer and the rate accelerates), etc. It can also cure the symptoms of gangrene caused by heat and poison injuring yin, yin deficiency and internal heat, and blood stasis. It can also treat stroke caused by yin deficiency and wind movement, toxic stasis and obstruction of collaterals, with hemiplegia (inability to move one side of the limb), numbness of one side of the body, unfavorable speech, red tongue, little moss, and fine pulse; ischemic stroke with the above symptoms. A small number of patients with gastrointestinal reactions such as nausea, epigastric fullness, loose stools (thin and unformed feces) after taking the drug. Pregnant women should be cautious; patients with cerebral hemorrhage should be cautious; patients with hemorrhagic disease or bleeding tendency should be cautious. If you need to use the drug is recommended to be used under the guidance of a traditional Chinese medicine practitioner to identify the evidence, unauthorized use of drugs may cause adverse consequences.