Particle implantation therapy for liver cancer has relatively good effect after surgery. Particle implantation technology for liver cancer treatment can accurately locate the lesion and accurately implant the particle dosage, maximally kill the cancer cells and minimize the damage to normal liver tissue, which is safe and effective and can prolong the survival time. Particle implantation has become one of the important methods of comprehensive treatment for malignant tumors. Particle implantation is feasible for early-stage hepatocellular carcinoma whose liver function or systemic condition can not tolerate surgery, those with portal vein thrombosis that can not be operated, early and middle-stage hepatocellular carcinoma that is unwilling to be operated, and middle and late-stage hepatocellular carcinoma that can not be resected because of losing surgical opportunities. Large tumor foci with a diameter of more than 5cm, multinodular foci with a number of more than 3, accompanied by a large amount of ascites, severe jaundice and poor coagulation function are not suitable for particle implantation treatment. In terms of specific effect, 125 iodine particle implantation combined with TACE for liver cancer treatment has been clinically studied to improve the efficacy, and 125 iodine particles can be implanted according to the shape and size of the tumor to achieve the purpose of controlling the tumor tissues and protecting the normal liver tissues in the surrounding area, effectively controlling the recurrence of the tumor in the liver, lowering the rate of extra-hepatic metastasis, and improving the long-term efficacy. Particle implantation requires professional operation, and in case of discomfort or other accidents, you should notify your doctor in time.