First, in patients with orbital wall fractures, especially infraorbital wall fractures, the eyeballs may sink so that the two eyes are not on the same line, which may be accompanied by double vision. Second, in patients with thyroid-related ophthalmopathy and hyperthyroidism proptosis, the affected eye is restricted in upward rotation and will show a downward shift, thus showing that the two eyes are not on the same line. Thirdly, eye displacement caused by tumor compression, which can be seen as intracranial occupancy, intraorbital occupancy or retrobulbar occupancy, etc. It is necessary to improve imaging examination to determine the location, size and nature of the tumor, so as to adopt conservative treatment or surgical treatment plan.