Wet age-related macular degeneration is a serious eye disease that threatens the eyesight of the elderly, and its development has its own pattern, divided into three stages, which we call the development trilogy: First: the neovascularization period. This is when the neovascularization has just formed and is still located under the retina and has not grown into the retinal tissue. These vessels are abnormal vessels, very brittle and prone to bleeding and exudation. Second: The neovascular growth phase. The neovascularization extends from under the retina, towards the retina, and invades into the real retinal tissue. And it leads to hemorrhage and exudation in the macula. Third: Scar-forming phase. During the continuous growth of the neovascularization, the fibrous tissue increases and the tissue eventually forms a fibrovascular scar. With the development of neovascularization, the patient’s symptoms go through the same corresponding three stages: In the early stage, vision is mildly reduced, mainly visual distortion and straight line becomes curved. In the middle stage, there is a significant loss of vision, with a fixed dark area in the middle of the visual field and a distinct sense of obscuration. In the late stage, vision is lost.