Callus on the feet is generally stimulated by friction after the formation of a horny layer hyperplasia, can be removed through life conditioning, hot water immersion, physical therapy and other ways. 1. Life conditioning: because the skin on the feet for a long time by the repeated friction of shoes, so that the local skin has keratin thickening. It is recommended to pay attention to the protection of foot skin, and wear loose, breathable and comfortable shoes. You can insist on the use of compound lactic acid cream or salicylic acid ointment and other drugs to soften the callus, so that the callus elimination. 2. Hot water soaking: You can use hot water to soak your feet to soften the calluses on your feet, and then use a foot grinding stone to rub off the cuticle on your feet. Then use the urea Vitamin E cream to apply locally to keep the feet moist and hydrated. 3. Physical therapy: If the callus on the foot is thicker, you can use carbon dioxide laser or liquid nitrogen freezing to destroy the abnormally thickened stratum corneum on the foot and remove the callus on the foot. It is recommended that patients with calluses on the feet pay attention to daily care, wear loose and comfortable shoes. You can go to the hospital, follow the doctor’s instructions for treatment, do not blindly use drugs.