Rhubarb is a Chinese herb whose main functions are to diarrhea heat and intestines, cool the blood and detoxify the toxins, and remove blood stasis and channels. The drug has a wide range of clinical applications and is very effective in treating both heat and stagnant symptoms. Rhubarb can be used clinically to treat constipation, abdominal pain, diarrhea, dysentery, jaundice, vomiting of blood, as well as red eyes, sore throat, and stomach pain, and skin diseases. Also bruises and burns can be treated with rhubarb. In addition, rhubarb is also useful in regulating amenorrhea and menstrual disorders in women. Rhubarb can treat upper gastrointestinal bleeding, and is most commonly used in clinical practice to treat constipation. Rhubarb and manganese can be well combined to form Da Cheng Qi Tang, which is very effective for stubborn constipation.