If you take antihypertensive drugs in the morning and your blood pressure is high in the evening, it means that the action time of the current antihypertensive drugs taken in the morning cannot be maintained into the evening, or the antihypertensive potency and antihypertensive dose of the current antihypertensive drugs are not enough. In order to better select antihypertensive drugs and determine the best time to take antihypertensive drugs, it is best to go to the hospital to check 24-hour ambulatory blood pressure to understand the pattern of blood pressure level changes over time and find the time period when blood pressure rises at night. About 1-2 hours before the rise in blood pressure, take an additional antihypertensive drug, commonly used amlodipine, nifedipine controlled-release tablets. After taking the medication, pay attention to rest or take a combination of medication in the morning, commonly used amlodipine combined with Irbesartan.