When liver cancer is diagnosed after 3 months of liver nodule, it is necessary to actively cooperate with doctor’s treatment, and common treatments are surgery, localized treatment, liver transplantation, drug treatment and so on. 1. Surgical treatment: Before surgery, doctors will evaluate liver functional reserve according to Child-Pugh score and indocyanine green 15-minute retention rate, and it is generally considered that Child-Pugh grade A~B and ICGR-15 <20%~30% are necessary conditions for taking surgical resection. 2. Local treatment: percutaneous puncture intratumoral injection of anhydrous ethanol is to inject anhydrous ethanol into liver cancer tissues to kill cancer cells, which is effective for liver cancer with diameter ≤2cm. Hepatic artery embolization is to inject embolic agent into the blood supplying artery of the tumor to block the blood supply of the tumor and make it necrotic. 3. Liver transplantation: Liver transplantation can remove the whole diseased liver, which is an effective means to treat liver cancer, but if the liver cancer has vascular invasion and distant metastasis, it is not suitable for liver transplantation. 4. Drug therapy: Sorafenib, a molecularly targeted multikinase inhibitor, is a molecularly targeted drug for the treatment of advanced liver cancer. Patients with hepatitis B virus infection need to take oral antiviral drugs such as entecavir. Patients should actively cooperate with doctors' treatment, combine with their own condition characteristics and adopt corresponding treatment plan under doctors' guidance.