With the improvement of China’s economic development level, the change of residents’ lifestyle and the acceleration of population aging, the number of obese people has increased significantly, and the trend is growing year by year. China is also a large country with diabetes, and some data show that the prevalence of diabetes among adults in China is as high as 11.6%, which is the highest in the world. It is well known that obesity and diabetes are closely related, and obese patients are prone to the occurrence of diabetes. This article elaborates on the relationship between obesity and diabetes and the precautions in daily life. First, obesity and diabetes relationship Overweight, obesity and abdominal fat accumulation is an important risk factor for the development of type 2 diabetes. A summary analysis of 240,000 population data in China shows that the prevalence of type 2 diabetes in people with BMI ≥ 24 is 2.0 times higher than that in people with BMI below 24, and the prevalence of type 2 diabetes in people with BMI ≥ 28 is 3.0 times higher than that in people with BMI below 24. The prevalence of diabetes was 2-2.5 times higher in men and women with a waist circumference of ≥85 cm and ≥80 cm, respectively, than in those with a normal waist circumference. It is more difficult for patients with type 2 diabetes combined with obesity to lose weight and maintain it than those who are obese alone. The phenomenon of insulin resistance (insulin insensitivity) and higher fasting insulin levels occur in obese patients with reduced number of insulin receptors and receptor defects, which affects glucose transport, utilization and protein synthesis. Weight loss can improve insulin resistance, lower blood glucose and improve risk factors for cardiovascular disease. A weight loss of 3% to 5% in overweight and obese patients with type 2 diabetes can result in clinically significant health benefits such as a significant reduction in blood glucose, lipids and blood pressure, and improved quality of life. In a certain range, the more weight loss, the greater the benefit. Second, obesity combined with diabetes on the human body when obesity and diabetes coexist, the impact on the heart, brain and kidney and other important organs will appear 1 + 1 > 2 effect. Obesity and diabetes exist other metabolic abnormalities synergistic effect can further aggravate the occurrence of chronic complications of type 2 diabetes patients. Obesity is an independent risk factor for diabetic nephropathy and can contribute to the deterioration of chronic kidney disease. Obesity in combination with type 2 diabetes increases the risk of cardiovascular disease. Therefore, for patients with type 2 diabetes combined with obesity, strengthening weight management while lowering glucose is of great significance to prevent diabetic complications and improve patients’ quality of life. Daily precautions for obesity combined with type 2 diabetes 1.Rational diet and calorie control For obese patients with type 2 diabetes, it is recommended to calculate according to 25-30 kcal/(kg standard weight-d), and long-term very low energy diet <800kcal/d is not recommended. Cultivate nutritionally balanced dietary habits, with protein intake at 15-20% of total energy, fat at less than 30% of total energy, and carbohydrate at 45-60% of total energy; long-term high protein diets are not recommended for overweight or obese people; intake of saturated fatty acids and trans fatty acids should be limited, and the proportion of vegetable fats in total fat intake should be increased; diets rich in omega-3 polyunsaturated fatty acids should be increased. Vegetable oil rich in ω-3 polyunsaturated fatty acids; limit cholesterol intake; ensure rich intake of vitamins, minerals and dietary fiber. 2, appropriate exercise, weight control Reasonable exercise can improve insulin sensitivity, skeletal muscle function, improve metabolic disorders, and have a positive feedback effect on improving the quality of life. Exercise prescription should include five major elements: exercise frequency, exercise intensity, exercise time, exercise type and exercise volume, and clinicians can be consulted in detail. The type of exercise should be mainly aerobic exercise. Note: Monitor blood sugar before and after exercise to prevent hypoglycemia, the key is self-monitoring and physician guidance. type 2 diabetes combined with obesity patients, exercise should pay attention to the prevention of joint pain and discomfort. 3, balanced mind, psychological intervention The dual pressure of obesity and diabetes further aggravates the psychological burden of patients. For obese or overweight type 2 diabetes patients should strengthen psychological intervention, through the psychological guidance of professional psychologists or diabetes specialists, to help patients gradually improve their lifestyles and build self-confidence. Reducing weight will not only reduce the psychological barriers of type 2 diabetic patients, but will also make it easier for many patients to regain confidence and improve life satisfaction from weight loss and exercise.