The approximate treatment cost of advanced bone metastasis of lung cancer is mainly related to the choice of treatment method and the treatment of adverse reaction, which ranges from several thousand dollars to tens of thousands of dollars, and the specific cost should also refer to the local hospital. When bone metastasis occurs in lung cancer, treatment methods mainly include surgery, radiotherapy, bisphosphonate therapy, targeted therapy and so on. Bone cementoplasty costs more, which may range from 30,000 to 40,000 dollars. Radiation therapy costs about between $10,000 and $20,000 dollars. Bisphosphonate therapy needs to be used every 28 days, and the cost will vary depending on the type of drug, costing between about 1,000 and 3,000 each time. Targeted therapy is mainly rituximab therapy, which costs about 20,000 yuan. Each local health insurance policy is different, some treatment in some areas in the health insurance reimbursement scope, may be relatively less out-of-pocket expenses, so the specific cost should also refer to the local hospital pricing.