Habitual miscarriages are those with more than 3 consecutive spontaneous miscarriages, and there are more and more habitual miscarriages among infertility patients, especially those with fetal sacs without fetal heartbeats in the early stage account for most of them, and we have adopted the method of immunotherapy to treat them with good results. Before doing immunotherapy, we should find out the causes, such as eugenics, antibodies, mycoplasma, chlamydia, infectious diseases, etc. Especially, those with positive closed antibody are indications for doing immunotherapy. Immunotherapy is simple, inexpensive and effective.