Patients with symptoms of chest pain when doing heavy work may be suffering from coronary atherosclerotic heart disease. Patients with coronary heart disease, due to the existence of coronary artery stenosis, when doing heavy work or strenuous exercise, there may be myocardial ischemia, resulting in angina pectoris symptoms, patients often have pain in the anterior region of the heart and accompanied by chest tightness, panic and other symptoms. Chest pain when doing heavy work may also be due to costochondritis, which is more common in young women, and patients tend to experience chest pain when taking a deep breath, coughing, or engaging in strenuous activities, and the pain may radiate to the upper limbs, armpits, or the back of the neck, resulting in radiating pain, which is prone to recurring episodes of pain. In addition, chest pain when doing heavy work may also be suffering from viral myocarditis, intercostal neuritis and other diseases. In this case, we should pay attention to rest, avoid exertion, avoid strenuous sports, and also need further examination to clarify the diagnosis, and according to the cause of the targeted treatment.