A raised pad of flesh underneath the big toe may be a callus, or it may be caused by corns, plantar warts and other diseases. 1. Callus: it is easy to occur in the foot, the cause of the disease is related to the uneven bone protrusion of the toe bone. Localized long-term extrusion, friction, can form foot pads. 2. Corns: the occurrence of corns is related to the extrusion and friction of the skin of the feet, resulting in localized conical thickening lesions. It may cause pain when walking, wearing shoes, or pressing with hands. 3. Plantar warts: Infection by the human papilloma virus leads to wart-like lesions on the skin of the soles of the feet or toes, and pads of flesh may appear under the big toe. Flesh pads protruding from the underside of the big toe, if significant pain occurs, you should also go to the hospital for examination to find out whether it is related to the pain caused by factors such as fasciitis, osteomalacia, gout, etc. It is recommended that you combine the treatment with your doctor’s advice.