Skin allergy is a common inflammatory reaction of the skin due to various allergic factors, and its manifestations are almost indistinguishable from those of hives and eczema. When skin allergy occurs in winter or summer, the main treatment measures are not different. To avoid contact with allergens as much as possible, patients can take oral antihistamines, such as loratadine, cetirizine, paracetamol, ibastine tablets, fexofenadine, etc. These are commonly used anti-allergy drugs with good effects. The vast majority of skin allergy patients can control their condition after taking these drugs for about 3-5 days. If local skin allergy occurs, patients can also apply glyburide lotion and glucocorticoid ointment topically, which can also effectively relieve the symptoms.