Nipple pain in mid-pregnancy is generally a normal physiological phenomenon and need not be overly concerned. Nipple pain in mid-pregnancy is generally due to the increase in estrogen and progesterone, which promotes the development of the milk ducts and follicles, and the breasts appear to be distended, swollen and itchy, which is a common phenomenon during pregnancy. This symptom is in preparation for postpartum breastfeeding, pregnant women do not need to be nervous, relax, you can use a warm towel to compress, can relieve the pain symptoms. Usually try to wear loose clothing to reduce the squeeze to the breast, keep the breast clean and hygienic, pregnant women in mid-pregnancy to do breast care every day, in order to prevent nipple rupture and lead to inflammation. In addition to normal physiological factors, it is not excluded that it is caused by mastitis and so on. If there is also a localized lump, nipple inversion, nipple overflow, or chills, high fever and other discomforts, you should consult a doctor in time to find out the cause, and treat the cause under the guidance of the doctor.